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Using the repository authors annotations, macrophage subsets (Supplementary Table 6) were combined for downstream analysis in Seurat v5

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And so that's sort of like the worst case scenario

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256 In addition, ethanol could activate kinase CK2 to phosphorylate MAT1 at Ser114, promote its interaction with PIN1 isomerase, inhibit MAT1 localization in mitochondria, and promote ethanol-induced mitochondrial dysfunction and fat accumulation